No obvious behavioral effects or overt alterations of heart rate or rhythm were noted in any of these horses after cocaine administration. The results of GC–MS analysis confirmed the presence of BZE above the limit of quantification (LOQ = 5 ng/mL) in urine samples collected from all four horses for up to 24 h after administration of 2.5 mg of cocaine and for up to 48 h after administration of 20 and 50 mg of cocaine.
The results of ELISA analysis of urine samples collected from all four horses suggested the presence of cocaine and/or its metabolites up to 10, 48, and 72 h after administration of 2.5, 20, and 50 mg of cocaine, respectively. In this study urine samples, collected from four horses following the administration of 2.5 and 20 mg of cocaine sublingually and 50 mg of cocaine intravenously, were analyzed for the presence of cocaine and/or its metabolites by enzyme-linked immunosorbent assay (ELISA) and gas chromatography–mass spectrometry (GC–MS). <100 ng/mL) of the primary cocaine metabolite, benzoylecgonine (BZE) have been detected in urine collected from horses competing in athletic events. Occasionally, very small concentrations (i.e. by direct titration of the basic component they determined the salts of cocaine, emetine, physostigmine, pilocarpine, scopolamine, and ethylmorphine, as well as salts of synthetic organic bases, i.e., procaine, percaine, pantocaine, and pethidine, using this unified method: approximately 0. Cocaine is a naturally occurring alkaloid that is commonly abused by human-beings for its psychostimulatory effects.
0 kommentar(er)
